Associations between very low concentrations of low density lipoprotein cholesterol, high sensitivity c-reactive protein, and health outcomes in the reasons for geographical and racial differences in stroke (regards) study
European Heart Journal Aug 31, 2018
Penson PE, et al. - In a free-living US population, researchers evaluated the association between low-density lipoprotein cholesterol (LDL-C), high sensitivity C-reactive protein (hs-CRP), and clinical outcomes. They selected individuals at “high risk” for coronary events with a Framingham Coronary Risk Score of ≥ 10% or atherosclerotic cardiovascular disease (ASCVD) risk ≥ 7.5%. An association of low hs-CRP with the reduced risk of incident stroke, incident CHD, and CHD death was seen, while there was no association of low LDL-C (<70 mg/dL) with any protective effects.
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