Fjellstad CM, et al. - Among patients with hand osteoarthritis (OA), researchers ascertained if ultrasound-detected grey-scale synovitis and power Doppler activity in the interphalangeal and 1^st carpometacarpal (CMC-1) joints was correlated with pain and physical function. Two hundred ninety patients with hand OA had an ultrasound examination of the bilateral interphalangeal and CMC-1 joints. Whether grade 0-3 grey-scale synovitis and power Doppler activity were associated with pain in the same joint were examined using logistic regression analyses with generalized estimating equations. Findings suggested an association of inflammation in both interphalangeal and CMC-1 joints with pain in the same joint. Nevertheless, correlations with hand pain, decreased physical function, and lower grip strength were present in the CMC-1 joints only for inflammation, indicating that reducing inflammation with CMC-1 is an important target for treatment.