Zhao YY, Javaheri S, Wang R, et al. - In a large multiethnic population sample, researchers used multivariable linear and logistic regression models to explore the relationships of snoring and several measurements of sleep apnea (SA) with subclinical carotid atherosclerosis. The sample consisted of 1,615 candidates (mean age was 68 years) from examination 5 (2010–2013) of the MESA study (Multi-Ethnic Study of Atherosclerosis). Using high-resolution B-mode ultrasound, carotid atherosclerosis was measured. Among younger but not older people, greater hypoxemia was linked to increased carotid intima-media thickness. Greater hypoxemia was related to increased carotid intima-media thickness in blacks in evaluating race-specific outcomes. Findings suggested an association of sleep disturbances with subclinical carotid atherosclerosis in both men and women, especially in those < 68 years of age. For carotid plaque and carotid intima-media thickness, the mechanisms underlying the relationship between SA and carotid atherosclerosis can differ.