Hutton JS, et al. - By performing this cross-sectional study with 47 healthy prekindergarten children (aged 3 to 5 years), researchers examined the integrity of brain white matter tracts supporting language and literacy skills in correlation with screen-based media use in preschool-aged children. The recruitment of the participants was done at a US children’s hospital and community primary care clinics. Among 69 recruited children, diffusion tensor imaging was completed by 47 (among whom 27 [57%] were girls, and the mean [SD] age was 54.3 [7.5] months). Findings revealed that screen use greater than that recommended by the American Academy of Pediatrics guidelines was related to lower microstructural integrity of brain white matter tracts supporting language and emergent literacy skills in prekindergarten children.