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Associations between polycystic ovary syndrome and adverse obstetric and neonatal outcomes: A population study of 9.1 million births

Human Reproduction Jul 15, 2020

Mills G, Badeghiesh A, Suarthana E, et al. - Researchers conducted an analysis of the Healthcare Cost and Utilization Project-Nationwide Inpatient Sample (HCUP-NIS) database in order to determine the risk for adverse delivery and neonatal outcomes attributable to polycystic ovary syndrome (PCOS). For this retrospective population-based cohort study, the HCUP-NIS database from 2004 to 2014 was assessed for deliveries to women with PCOS as part of the study group (n = 14,882), and to those with non-PCOS births that comprised the reference group (n = 9,081,906). Observations revealed that women with PCOS more frequently experienced preterm prelabour rupture of membranes, preterm delivery and placental abruption as well as more frequently had chorioamnionitis, postpartum maternal infections and delivery by cesarean section, after controlling for all potential confounding effects.

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