Dotan E, Tew WP, Mohile SG, et al. - Given that morbidity and mortality in older adults with cancer can be directly influenced by nutritional status, researchers assessed the link between pretreatment BMI, albumin level, and unintentional weight loss (UWL) in the prior 6 months and chemotherapy toxicity in older adults having solid tumors in this secondary investigation of a prospective, multicenter research including chemotherapy-treated patients 65 years old or older. Experts found no link between > 10% UWL and risk for grade 3+ chemotherapy toxicity, in multivariable analysis. In multivariable analysis, a trend toward a link between a BMI ≥ 30 kg/m² and a reduced risk of grade 3+ chemotherapy toxicity was evident, whereas a higher risk of grade 3+ chemotherapy toxicity was observed in relation to a low albumin level (≤ 3.6 mg/dL). Findings revealed a lower risk of grade 3+ chemotherapy toxicity in relation to higher BMIs and normal albumin levels among older adults with solid tumors.