Neuman J, et al. - Given that the mean systemic filling pressure may afford a physiologically more accurate estimate of renal venous pressure and renal perfusion pressure but its link with cardiac surgery‐associated acute kidney injury (CSA‐AKI) has not been described, therefore, researchers explored this topic in this study with patients admitted to ICU after cardiac surgery without pre‐operative renal dysfunction. Mean arterial pressure and central venous pressure and cardiac output were monitored to compute the mean systemic filling pressure analogue (P_msa). CSA‐AKI was defined using AKI‐KDIGO guidelines. According to findings, P_msa in post‐operative cardiac surgery patients was shown to be related to CSA‐AKI occurrence also when included into estimates of renal perfusion pressure.