Aulich J, Cho YH, Januszewski AS, et al. - Researchers sought to ascertain the relative contribution of inflammation in common types of diabetes in youth: type 1 diabetes (T1D), type 2 diabetes (T2D), and cystic fibrosis-related diabetes (CFRD) via examining inflammatory markers by diabetes type and complication status, and appraising indicators of inflammation and complications. They conducted a cross-sectional study of 134 T1D, 32 T2D, 32 CFRD and 48 individuals without diabetes (including 11 with CF and normal glucose tolerance). Assessment of inflammation was done by sE-selectin by ELISA, hsCRP by turbidimetry, WCC and ESR. Adolescents with diabetes had raised circulating inflammatory markers, being higher and comparable in T2D and CFRD than in T1D. They observed an independent association of inflammation with diabetes complications; this was consistent with inflammation driving vascular pathology in diabetes.