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Associations among body mass index, cortical thickness, and executive function in children

JAMA Pediatrics Feb 07, 2020

Laurent JS, Watts R, Adise S, et al. - Researchers conducted this cross-sectional study to ascertain if BMI was correlated with thickness of the cerebral cortex and if cortical thickness mediates the connection between BMI and executive function in children. Of 3,190 people (mean [SD] age was 10.0 [0.61] years), those with higher BMI had lower cortical thickness. Findings suggested an association of higher BMI with the thinner cortex, particularly in the prefrontal cortex. The correlation between BMI and working memory was partly mediated by the thickness of the prefrontal cortex. Such results suggest the correlation of BMI with cortical development and diminished executive functions like working memory.
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