Association of weight gain acceleration with risk of retinopathy of prematurity
JAMA Nov 26, 2019
Bal S, et al. - In this secondary analysis of data from the Postnatal Growth and Retinopathy of Prematurity (G-ROP) study, researchers ascertained if faster WGA during a later postnatal period was correlated with a higher, rather than lower, risk of severe ROP. The sample consisted of 6,835 infants undergoing ROP examinations from 29 hospitals in North America from January 2006 to June 2012. From September to December 2016, data were analyzed. With the exception of infants with the slowest early postnatal weight gain, increased acceleration of late weight gain was related to increased risk of severe ROP up to a threshold above which risk dropped. While early slow weight gain is related to increased risk of ROP, the connection seems more complex than previously thought, as the acceleration of timing and rate of weight gain may also influence the risk of severe ROP.
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