Wink AE, Gross KD, Brown CA, et al. - Among older adults with or at risk of osteoarthritis (OA), researchers studied the 2-year correlation of varus knee thrust observed during walking to the odds of worsening Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) knee pain. They used logistic regression to estimate the odds of worsening knee pain (defined as either any increase in WOMAC score or as clinically important worsening), adjusting for age, gender, race, BMI, clinic site, gait speed, and static knee alignment. In total, 1,623 candidates contributed 3,204 knees. In 31.5% of knees, the varus thrust was observed. Risk factor for worsening and incident knee pain was varus thrust. Targeting varus thrust through non-invasive therapies may prevent knee pain from developing or worsening in older adults with or at risk of knee OA.