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Association of Tourette syndrome and chronic tic disorder with cervical spine disorders and related neurological complications

JAMA Aug 27, 2021

Isung J, Isomura K, Larsson H, et al. - According to this matched cohort study, cervical spine disorders are more common in those with severe Tourette syndrome or chronic tic disorder (TS/CTD). Such consequences are uncommon, but they can cause long-term disability in some people, necessitating continuous monitoring to allow for early intervention.

  • In total, 6,791 people with TS/CTD were identified (5,238 [77.1%] were male; median [interquartile] age at first diagnosis, 15.6 [11.4-23.7] years) and matched to 67,910 unexposed individuals.

  • Individuals who were exposed had a 39% higher chance of developing a cervical spine disorder.

  • Cervical vascular and nonvascular disorders had adjusted hazard ratios of 1.57 and 1.38, respectively.

  • Both men and women faced identical risks.

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