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Association of timing of initiation of pharmacologic venous thromboembolism prophylaxis with outcomes in trauma patients

The Journal of Trauma and Acute Care Surgery Dec 25, 2020

Hecht JP, Han EJ, Cain-Nielsen AH, et al. - Risk for developing venous thromboembolism (VTE) is high in patients with traumatic injury. In this study, the association between timing of initiation of pharmacologic prophylaxis with VTE complications was examined via analyzing trauma quality collaborative data from 34 American College of Surgeons Committee on Trauma–verified levels I and II trauma centers. Researchers here analyzed 79,386 patients. Among these patients, 1,495 (1.9%) experienced a VTE complication and 1,437 (1.8%) died. Findings suggest lower rates of VTE in correlation with early initiation of pharmacologic VTE prophylaxis in stable trauma patients.

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