Sun X, Chen L, Wu R, et al. - Among euthyroid male patients with type 2 diabetes mellitus (T2DM), changes in thyroid hormones were identified to be linked with various body fat content and lipid metabolism.

• In this cross sectional analysis, 66 male patients with T2DM who were ≥ 18.0 years and had normal thyroid function were analyzed (mean free triiodothyronine [FT3], free thyroxine [FT4], and thyroid-stimulating hormone [TSH] were 2.56 pg/mL, 1.03 ng/dL, and 1.50 μIU/mL, respectively).

• Elevated FT3 were found to be related to higher body mass index (BMI), body fat percentage (BFP), visceral fat content (VFC), adiponectin, tumor necrosis factor alpha (TNF-α), and interleukin 6 (IL-6).

• Elevated TSH could raise the total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C).

• Positive correlation of FT3 with BMI, waist–hip ratio, BFP, VFC, adiponectin, TNF-α, and IL-6 was evident.

• FT4 was shown to be positively correlated with HDL-C, LDL-C, and adiponectin.

• A positive correlation existed between TSH and TC.