Li P, Ding L, Zhen J, et al. - Presence of subclinical hyperthyroidism confers an independent risk for presarcopenia in type 2 diabetes mellitus (T2DM). This is not true for subclinical hypothyroidism.

• A cross-sectional study of 1,865 adult patients with T2DM.

• T2DM patients with subclinical hyperthyroidism, but not those with subclinical hypothyroidism, exhibited an increased odds of presarcopenia (multivariate-adjusted odds ratio) = 1.99), vs the euthyroid group (Euthy).

• Independent risk factors for presarcopenia in the subclinical hyperthyroidism group were age and BMI < 24kg/m ² .

• A high FT4/FT3 ratio was revealed as a good index of presarcopenia in addition to the elderly, in the Euthy group with T2DM.