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Association of statins and 28-day mortality in patients hospitalized with SARS CoV-2 infection

The Journal of Infectious Diseases Oct 26, 2021

Memel ZN, Lee JJ, Foulkes AS, et al. - In patients hospitalized with SARS-CoV-2 infection, in-hospital statin use resulted in reduced 28-day mortality.

  • A cohort study of 1,179 patients with SARS-CoV-2, divided into 4 groups: those who took statins before hospitalization (continued, discontinued) and those who did not (newly initiated, never).

  • A decreased hazard of death was reported in relation to inpatient statin use (HR 0.566).

  • This relationship held in those who did and did not receive statins prior to hospitalization (HRs 0.270 and 0.493).

  • Statin use conferred improved time-to-death for patients >65 years, but not those ≤65 years.

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