Larsson SC, et al. - According to this Mendelian randomization analysis, increased serum magnesium concentrations minimize the incidence of intracranial aneurysm and accompanying hemorrhage. Such findings add to a growing body of evidence that suggests a higher magnesium intake can help avoid cerebrovascular and cardiovascular disorders.

• A decreased incidence of the intracranial aneurysm was linked to higher genetically predicted serum magnesium concentrations.

• The odds ratios for intracranial aneurysm (unruptured and ruptured combined) were 0.66, 0.57 for unruptured intracranial aneurysm, and 0.67 for aneurysmal subarachnoid hemorrhage per 0.1 mmol/L increase in genetically predicted serum magnesium concentrations.