Association of serum lipid parameters with the scorad index and onset of atopic dermatitis in children
Pediatric Allergy and Immunology Nov 05, 2020
Kim JH, Lee SW, Yon DK, et al. - This research was sought to evaluate the relationship between dyslipidemia and atopic dermatitis in children by analysis of disease onset, risk factors, and disease severity. Subset I analyzed 7‐year‐old children in elementary school (n = 248), and Subset II was a retrospective long‐term follow‐up hospital‐based study that included a total of 52,725 between 1986 and 2016 that applied propensity score matching. The Subset I study ascertained total cholesterol (TC), high‐density lipoprotein cholesterol, low‐density lipoprotein cholesterol, and triglycerides, and the Scoring Atopic Dermatitis (SCORAD) index was also determined. They determined the time of atopic dermatitis onset for asymptomatic subjects whose TC levels were below or above 170 mg/d in the Subset II study. It was reported that in children, an abnormal blood lipid profile is associated with the presence of atopic dermatitis and the SCORAD index. They found a greater risk of atopic dermatitis onset with high levels of TC.
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