Association of serum carbohydrate antigen 19-9 level with arterial stiffness and coronary artery calcification in middle-aged and older adults: A cross-sectional study
Journal of Hypertension Dec 09, 2019
Park B, et al. - Researchers performed this cross-sectional analysis to investigate if there exists a link between serum carbohydrate antigen 19-9 level and atherosclerosis as measured by brachial–ankle pulse wave velocity (PWV) and coronary calcium score (CCS). The participants were 1,732 Korean adults with the age of at least 45 years who underwent a health examination program. By means of chemiluminescence immunoassay, they quantified serum carbohydrate antigen 19-9 level, which was then classified as quartiles, following the elimination of individuals with carbohydrate antigen 19-9 levels more than 30 U/ml to rule out hidden malignancy. They noted a rise in the prevalence of high PWV and high CCS with serum carbohydrate antigen 19-9 quartile. Findings revealed a positive as well as independent link of serum carbohydrate antigen 19-9 level with arterial stiffness and coronary artery calcification.
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