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Association of retinal vascular occlusion with women filling a prescription for female hormone therapy

JAMA Ophthalmology Jan 24, 2021

Song D, Nadelmann J, Yu Y, et al. - Using an administrative claims insurance database, researchers performed this multiple-cohort study to assess whether filling a prescription of female hormone therapy (FHT) is correlated with an increased risk of retinal artery occlusion (RAO) or retinal vein occlusions (RVO). In total, 205,304 women who filled a prescription for FHT were matched to 755,462 control people. Subanalyses that stratified by age, diabetes, and hypertension similarly displayed no significant connections between the FHT prescription cohort and all outcomes. These results indicate that the risk of RAO or RVO is not increased by filling a prescription for FHT and possibly taking FHT. In the assessment of an individual with an RAO or RVO, such history may not be important, nor do the findings support stopping FHT in an individual who causes an RAO or RVO.

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