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Association of radial artery graft vs saphenous vein graft with long-term cardiovascular outcomes among patients undergoing coronary artery bypass grafting: A systematic review and meta-analysis

JAMA Jul 17, 2020

Gaudino M, Benedetto U, Fremes S, et al. - Researchers investigated risk of adverse cardiac events in the long term in correlation with using the radial artery instead of the saphenous vein for coronary artery bypass surgery. They conducted individual participant data meta-analysis from 5 randomized clinical trials including 1,036 patients undergoing coronary artery bypass grafting. The radial artery group comprised 376 [70.4%] men vs 351 [69.9%] in the saphenous vein group; mean age was 66.6 years in the radial artery group vs 67.1 years in the saphenous vein group. They identified correlation of randomization to receive radial artery vs saphenous vein graft with an incidence of a composite of death, myocardial infarction, or repeat revascularization of 41 vs 47 events per 1,000 person-years after a median follow-up of 10 years, a difference that was statistically significant. Findings thereby suggest an association of radial artery graft, vs saphenous vein graft, with a lower risk of a composite of cardiovascular outcomes.

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