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Association of QRS-T angle and heart rate variability with major cardiac events and mortality in hemodialysis patients

Annals of Noninvasive Electrocardiology Jun 29, 2018

Poulikakos D, et al. - In a previous pilot study, researchers demonstrated that intradialytic electrocardiographic (ECG) monitoring can produce stable profiles of selected repolarization descriptors and heart rate variability (HRV) parameters. In this present study, they investigated the correlation of major adverse cardiac events (MACE) and mortality with these ECG markers. They found that in patients who died vs survivors and in those who were MACE positive vs negative, total cosine R to T (TCRT) (in degrees) was higher and low-frequency (LF)/high-frequency (HF) was lower. TCRT and LF/HF were identified as significant predictors in multivariate Cox regression analysis of mortality risk adjusted for age, diabetes mellitus, and coronary artery disease.

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