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Association of prenatal opioid exposure with precentral gyrus volume in children

JAMA Jun 12, 2020

Hartwell ML, Croff JM, Morris AS, et al. - There was a correlation of prenatal opioid exposure and delayed locomotor performance at multiple stages of early child development and with smaller neuroanatomical structures, such as the basal ganglia. The motor cortex, which controls speech and motor skills, may also be vulnerable to drug exposure, but to the authors' knowledge, this has yet to be evaluated. This study demonstrate that distinguishing risks of exposure correlated with brain structures is critical for prevention and intervention planning for cognitive impacts that can last long after conception.

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