Pugliese L, Spiritigliozzi L, Di Tosto F, et al. - Researchers examined the link of plaque calcification pattern and attenuation with plaque instability characteristics, coronary artery disease (CAD) grade and coronary artery calcium score (CACS). Participants were 100 patients with coronary stenosis related to calcified plaques. Experts identified higher stenosis and CACS grade [and epicardial adipose tissue (EAT) attenuation] but lower plaque instability score among patients with large calcification pattern or higher plaque calcification attenuation, whereas they detected lower stenosis and CACS grade (and EAT attenuation) but higher plaque instability score in patients with spotty calcification pattern or lower plaque calcification attenuation. Based on the findings, experts recommended considering both the pattern and attenuation of calcification, besides CACS, for risk stratification of heavily calcified high-risk patients with non-critical coronary stenosis.