Davies JC, Hugh S, Rich JT, et al. - In this multicenter collaborative cohort study, experts aspired to explore whether pharyngocutaneous fistula after salvage laryngectomy is correlated with locoregional and distant control, disease-free survival, and/or overall survival. Between January 1, 2000, and December 31, 2014, 550 patients (mean [SD] age, 64 [10.4] years; men, 465 [85%]) who underwent salvage laryngectomy for recurrent laryngeal cancer were analyzed. According to results, the rate of distant metastatic disease was 13% higher in patients who developed pharyngocutaneous fistula after salvage laryngectomy. The development of pharyngocutaneous fistula after salvage laryngectomy is linked to an increased risk of distant metastases.