Sheiban I, Ge Z, Kan J, et al. - In this study using five definitions of periprocedural myocardial infarction (PMI) post-percutaneous coronary intervention (PCI), it was found that PMI rate varied with the definition post-stenting for bifurcation lesions. A strong correlation was found between PMI defined by SCAI and EXCEL definitions and adjusted all-cause and cardiac death.

• Analysis of DKCRUSH studies was performed to understand the correlation between PMI and mortality in bifurcation lesions.

• SYNTAX, Fourth Universal Definition of MI (4th UDMI), ISCHEMIA, SCAI, and EXCEL definitions were applied to describe PMI.

• Participants were 1300 patients with both CK and creatine kinase-myocardial band (CK-MB) recordings pre- and post-stenting.

• PMI occurrence in 21 (1.6%), 56 (4.3%), 29 (2.2%), and 32 (2.5%) patients was found on applying SYNTAX, 4th UDMI or ISCHEMIA, SCAI, and EXCEL definitions, respectively.

• At the end of follow-up, but not at 30 days or 1-year after stenting, there was a significant correlation of all definitions with unadjusted mortality.

• The correlation of CK-MB values with mortality was strongly enhanced by CK-MB ≥ 5 x UNL.