Association of parental myopia with higher risk of myopia among multiethnic children before school age
JAMA Ophthalmology May 18, 2020
Jiang X, Tarczy-Hornoch K, Cotter SA, et al. - In multiethnic children aged 6 to 72 months, researchers explored the correlation of parental myopia with refractive error and ocular biometry. The analysis cohort comprised 9,793 children, including 4,003 Asian, 2,201 African American, 1,998 Hispanic white, and 1,591 non-Hispanic white candidates (5,106 boys [52.1%]; mean [SD] age, 40.0 [18.9] months). Findings suggested an association of parental myopia, particularly childhood-onset parental myopia, with an increased risk of early-onset myopia in Asian, Hispanic, non-Hispanic white, and African American children. The observed associations of parental myopia in children as early as 1 year of age and in children without myopia indicate that genetic susceptibility may play a greater role in early-onset myopia and that parental myopia may lead to myopia in children by creating a more myopic baseline before school age.
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