McAdow M, et al. - Researchers performed a retrospective cohort analysis to explore the connection between temporary cessation in oxytocin infusion (oxytocin rest) and mode of delivery in women undergoing induction of labor with a protracted latent phase. The sample consisted of nulliparous women with term, vertex, singleton gestations who were undergoing induction of labor with continuous oxytocin infusion at a large academic medical center. One thousand one hundred ninety-three patients met eligibility criteria from January 2012 to December 2016. The odds ratios of cesarean delivery for patients with oxytocin rest vs those with no oxytocin rest were as follows after adjusting for potential confounders: 1.12 for less than 1 hour, 0.78 for 1–2 hours, 0.60 for 2–8 hours, and 0.43 for 8 hours or more. A clinical tool that can reduce the risk of cesarean delivery among women with protracted latent labor without significantly increasing maternal or neonatal morbidity, is an oxytocin rest of at least 8 hours. No association was found between oxytocin rest of more than 8 hours and a composite of maternal or neonatal morbidities.