Shafi S, et al. - Researchers aimed at assessing the incidence of opioid-related adverse drug events (ORADEs) in patients undergoing hospital-based surgical and endoscopic procedures. In addition, they determined the association of ORADEs with clinical and cost outcomes. Clinical and administrative data of 135,379 patients were studied identifying 14,386 (10.6%) patients who experienced ORADEs. Observations suggested these events to be correlated with significantly worse patient outcomes, including increased inpatient mortality, greater likelihood of discharge to another care facility, prolonged length of stay, high cost of hospitalization, and higher rate of 30-day readmission.