Chua KP, Harbaugh CM, Brummett CM, et al. - From the database of a large national private insurer in the US, this cohort analysis used the 2016 to 2017 claims data to evaluate national perioperative opioid prescribing patterns, clinical and demographic factors correlated with these patterns, and relationship between these patterns and complications in children after tonsillectomy vs children not using opioids. The study sample consisted of 15,793 children [mean (SD) age was 7.8 (4.2) years] who had a tonsillectomy. According to findings, having 1 or more perioperative fills was not correlated with return visits for pain or dehydration or secondary hemorrhage vs children not using opioids, but it was related to increased risk of return visits for constipation. Findings suggested no association of duration with return visits for complications. In children after tonsillectomy, such results potentially support the feasibility of decreasing perioperative opioid prescribing and prescription duration.