Kim JY, et al. - Researchers explored the connection between obstructive sleep apnea (OSA) and the development of affective disorders in this cohort study using a Korean nationwide representative sample of 2004 through 2006 data on 985 people (aged < 45 years). During a 9-year follow-up, the overall incidence of affective disorder (ie, depression and anxiety) was higher in the OSA group than in the comparison group. In patients with OSA, the adjusted hazard ratio for depression and anxiety development appears to be higher in females than in males with OSA. Findings suggested an association of OSA with an increased incidence of affective disorder. Further studies seem to be required to verify the results and, if validated, then studies are required to investigate the nature of the observed connection between OSA and affective symptoms, including potential causality.