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Association of obstructive sleep apnea with severity of patients hospitalized for acute asthma

Annals of Allergy, Asthma, and Immunology Nov 22, 2019

Oka S, et al. - By performing this retrospective cohort analysis, researchers tried to understand the link between obstructive sleep apnea (OSA) and acute asthma severity, by utilizing State Inpatient Databases from eight geographically-diverse US states, 2010-2013. They assessed markers of acute severity—mechanical ventilation use, hospital length-of-stay (LOS), and inhospital mortality as the outcomes. They also fitted multivariable logistic regression models adjusting for age, gender, race/ethnicity, primary insurance, household income, patient residence, comorbidities, hospital state, and hospitalization year, to define the link of interest. There were 73,408 adult patients who were hospitalized for acute asthma, among these, OSA was present in 10.3%. A higher risk of non-invasive positive pressure ventilation use and longer LOS was reported in relation to OSA vs those without OSA in this study sample of patients hospitalized for acute asthma.
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