Association of mineral bone disorder with decline in residual kidney function in incident hemodialysis patients
Journal of Bone and Mineral Research Nov 17, 2019
Lee YJ, Okuda Y, Sy J, et al. - In this retrospective cohort study, researchers explored the connection of baseline serum phosphorus, calcium, intact parathyroid hormone (PTH), and alkaline phosphatase (ALP) with a decline in residual kidney function (RKF). Participants in the study were 13,772 individuals who started conventional hemodialysis (HD) during 2007–2011 and survived 6 months of dialysis. The authors discovered that the increased number of deviations in parameters had an additive effect on RKF's decline. Mineral bone disorder parameter abnormalities including higher phosphorus, intact PTH, and ALP and lower calcium levels were independently related to a decline in RKF in incident HD patients.
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