Association of mineral bone disorder with decline in residual kidney function in incident hemodialysis patients
Journal of Bone and Mineral Research Oct 25, 2019
Lee YJ, Okuda Y, Sy J, et al. - In this retrospective cohort study involving 13,772 individuals who started conventional hemodialysis (HD) during 2007–2011 and survived 6 months of dialysis, researchers analyzed the relationship of baseline serum phosphorus levels with a decline in residual kidney function (RKF), as well as explored the connection of baseline calcium, intact parathyroid hormone (PTH), and alkaline phosphatase (ALP) levels with a decline in RKF. Investigators found that the increased number of deviations in parameters had an additive effect on RKF's decline. Mineral bone disorder parameter abnormalities including higher phosphorus, intact PTH, and ALP and lower calcium levels were independently correlated with a decline in RKF in incident HD patients.
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