Armstrong NM, et al. - Using data from the Baltimore Longitudinal Study of Aging, researchers assessed the correlation of midlife hearing impairment (HI) with brain volume trajectories in later life (≥65 years of age). The study sample consisted of 194 subjects (mean [SD] age at hearing assessment, 54.5 [10.0] years; 106 [54.6%] female; 169 [87.1%] white). Findings suggested an association of midlife HI in the better ear with volumetric declines in the right hippocampus and left entorhinal cortex. According to this prospective cohort study, a risk factor for temporal lobe volume loss is midlife HI. A poorer midlife hearing was linked to declines in the hippocampus and entorhinal cortex, especially in the right ear.