Saito-Abe M, Yamamoto-Hanada K, Pak K, et al. - Researchers used a nationwide birth cohort to assess the links between allergic characteristics among mothers and preterm pregnancy outcomes. Data from pregnant women collected from the Japanese Environment and Children’s Study, a nationwide general birth cohort study, were examined. This analysis involved 97,683 pregnant women. The estimated prevalence of preterm birth, threatened preterm labor (TPL), and preterm premature rupture of the membrane was 4.7, 19.6, and 1.2%, respectively. An elevated risk of TPL was observed in relation to maternal history of allergic diseases (asthma, allergic rhinitis, allergic conjunctivitis, food allergy, drug allergy, and contact dermatitis). Although a negative link with preterm birth was shown by some maternal allergic features, the variables impacting preterm birth varied by the gestational age of the fetus (22–33 weeks vs 34–36 weeks). Overall, experts inferred that the risk of TPL may be raised by maternal allergic disease, except atopic dermatitis.