Association of maternal allergy with human milk soluble CD14 and fatty acids, and early childhood atopic dermatitis
Pediatric Allergy and Immunology Feb 15, 2019
Hua MC, et al. - Via analyzing 443 mother-child groups (445 children) enrolled in the Prediction of Allergies in Taiwanese Children birth cohort study, researchers investigated if maternal allergy is associated with soluble CD14 (sCD14) and fatty acid composition in different stages of lactation and the onset of atopic dermatitis (AD) in early childhood. Allergies were reported in 185 (41.8%) mothers, and physician-diagnosed AD was noted in 154 (34.6%) children by the age of 2 years. Findings suggest an association of decreased sCD14 levels in the colostrum and mature milk at 2 months postpartum (2-month HM) with AD at 2 years of age, particularly among children born to mothers with allergies.
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