Carlesso LC, Hawker GA, Torner J, et al. - This study was intended to analyze the relation of knee pain patterns to pain severity and to radiographic osteoarthritis (OA) severity and duration. Researchers designed a Multicenter Osteoarthritis Study that was a longitudinal cohort of older adults with or at risk of knee OA. Using regression models with generalized estimating equations, they evaluated the relation of Intermittent and constant osteoarthritis pain patterns to knee pain severity, radiographic knee OA (ROA) severity, and ROA duration. A total of 2,322 individuals were included in the study (mean age 68.8 years, body mass index 31.0 kg/m ², 60% female). It was shown that knee pain patterns are correlated with radiographic disease stage and duration, as well as pain severity, indicating the fact that pain patterns are important for understanding symptomatic disease progression.