Bierstone D, et al. - Authors investigated the correlation between histologic chorioamnionitis among neonates born very preterm with intraventricular hemorrhage (IVH) and punctate white matter injury (WMI) or with adverse neurodevelopmental outcomes during early childhood among children who were born preterm (24-32 weeks’ gestation) and who had undergone a placental pathologic evaluation, magnetic resonance imaging as soon as clinically stable, and Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III) assessments between 18 and 24 months’ corrected age (CA). After accounting for perinatal factors, no link was determined between histologic chorioamnionitis with IVH or WMI near birth or with worse cognitive or motor outcomes from 18 to 24 months’ CA. Data displayed that the postnatal factors attenuated the connection between chorioamnionitis and neurodevelopmental outcomes. This, in turn, underscored the significance of preventing postnatal illness, such as infection, to promote optimal outcomes among children born preterm.