Wysham KD, et al. - Authors gauged the contributions of rheumatoid arthritis (RA) characteristics, medication use, and body composition to low bone mineral density (BMD) in patients with RA. Findings suggested a strong association of high anti-CCP positivity and ALMI with BMD in patients with RA. The presumption that processes specific to RA negatively impact BMD was supported by the linear relationship of anti-CCP levels with lower BMD. On the contrary, experts noted a positive association of ALMI with BMD, suggesting the importance of this potentially modifiable risk factor. The complicated interplay of RA disease-specific and functional factors and their impact on bone mass were demonstrated in the results.