Kundi H, Wadhera RK, Strom JB, et al. - Researchers performed this nationwide cohort study to investigate if an improved prediction of outcomes for patients with acute myocardial infarction (AMI), heart failure (HF), and pneumonia could be obtained by adding frailty measures to conventional comorbidity-based risk-adjustment models. Participants (n = 785,127) were Medicare fee-for-service beneficiaries 65 years and older in the US between January 1 and December 1, 2016. For 30-day results across all conditions, they assessed the incremental influence of adding the Hospital Frailty Risk Score (HFRS) to current comorbidity-based risk-adjustment models. In this study sample of Medicare fee-for-service beneficiaries, findings revealed the link of frailty, as measured by the HFRS, with mortality and readmissions in patients hospitalized for AMI, HF, or pneumonia. An improved prediction of outcomes for all 3 conditions was achieved with the addition of HFRS to traditional comorbidity-based risk-prediction models.