Niziol LM, et al. - In this post hoc analysis of 607 participants from the Collaborative Initial Glaucoma Treatment Study, researchers evaluated the time between initial glaucoma treatment of the study eye (SE) and the need for treatment of the fellow eye (FE). They also ascertained the concordance between rates of progression in SEs and FEs. Nearly one-half of patients with newly diagnosed open-angle glaucoma had initial treatment of both eyes. In addition, approximately two-thirds of patients had bilateral treatment after 7 years. They found that the probability of FE treatment for open-angle glaucoma was 0.57 at 1 year and 0.68 at 7 years post-randomization. Hypertension and intraocular pressure were included in the modifiable factors out of the variables predictive of FE treatment. Slopes of mean deviation were comparable between SEs and treated FEs. Overall, findings indicated that SE change is a harbinger of FE change and needs close surveillance.