Tap L, et al. - The possible relationship between estimated glomerular filtration rate (eGFR) and multiple elements of physical performance was investigated in older fallers. Older fallers with an eGFR ≥ 90 ml/min were found to have smaller calf circumference and up to 10% lower handgrip strength compared to those with a reduced eGFR. This lower muscle mass was likely to lead to an overestimation of kidney function. Therefore, this outcome supported the search for biomarkers independent of muscle mass to estimate kidney function in older persons.