Association of epidural labor analgesia with offspring risk of autism spectrum disorders
JAMA Apr 22, 2021
Wall-Wieler E, Bateman BT, Hanlon-Dearman A, et al. - Researchers conducted a longitudinal cohort study of vaginal deliveries of singleton live infants born from 2005 to 2016 with the aim to determine the correlation between epidural labor analgesia (ELA) and offspring risk of autism spectrum disorder (ASD).This cohort study included a total of 123,175 offspring born in Manitoba, Canada, from 2005 to 2016. Findings revealed no correlation of ELA exposure with an increased risk of ASD in offspring after accounting for maternal sociodemographic, preexisting, pregnancy-related, and birth-specific factors.
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