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Association of diastolic blood pressure with survival during paediatric cardiopulmonary resuscitation

Resuscitation Aug 08, 2019

O’Brien CE, et al. - Researchers investigated how survival is correlated with diastolic blood pressure (DBP) throughout resuscitation from pediatric asphyxial cardiac arrest via performing a retrospective, secondary analysis of 200 swine resuscitations. Following asphyxial cardiac arrest, swine were resuscitated with predefined periods of basic and advanced life support (BLS and ALS, respectively) and were assessed for DBP every 30 s. Twenty minutes sustained return of spontaneous circulation (ROSC) was defined as survival. A higher DBP was observed throughout resuscitation in correlation with survival after asphyxial cardiac arrest, but a reduction in the difference between survivors and non-survivors was noted following prolonged BLS. During ALS, survival and time to ROSC were observed to be correlated with response to adrenaline administration. In case of clinical confirmation, these findings may help in titrating adrenaline during resuscitation and prognosticating likelihood of ROSC.
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