Zhang HW, Jin JL, Cao YX, et al. - A worse outcome was experienced by diabetic patients with intermediate coronary artery stenosis (ICAS) which was comparable to patients suffering from severe coronary artery stenosis (SCAS) alone.

• This study involved 10,940 patients who were hospitalized due to angina-like chest pain, and were divided into non-obstructive coronary artery stenosis (CAS) (NOCAS, < 50% stenosis), intermediate CAS (50–69% stenosis), and severe CAS (70–100% stenosis) subgroups.

• Participants were further split into six groups: NOCAS with diabetes mellitus (DM) and non-DM, ICAS with DM and non-DM, and SCAS with DM and non-DM.

• A higher incidence of major adverse cardiovascular events was observed in those with ICAS or SCAS when patients coexisted with DM.

• Increased risk of events was observed in patients with ICAS and DM, SCAS and non-DM, SCAS and DM [adjusted hazard ratio: 1.709, 1.911, 2.053] vs those with NOCAS and non-DM.