Petkovic-Curcin A, et al. - The present study was designed to examine whether polymorphisms of a cluster of differentiation 14 (CD14), tumor necrosis factor alpha (TNFα), interleukin (IL)6, IL10, and IL1ra genes were correlated with the risk of peri-implantitis susceptibility in patients with dental implants in the Serbian population. The findings implied that smoking and the presence of TNFα-308 GA/AA genotypes could increase the risk for peri-implantitis, while CD14-159 polymorphic CT/TT genotypes reduced the risk. Furthermore, in the Serbian population, the results indicated a significant association of CD14-159, TNFα-308, and IL6-174 genotypes and clinical parameters. However, to confirm these observations, future studies in larger patient groups were necessary.