Association of Controlling Nutritional Status score with 2-year clinical outcomes in patients with ST elevation myocardial infarction undergoing primary percutaneous coronary intervention
Heart, Lung, and Circulation Apr 18, 2020
Deng X, Zhang S, Shen S, et al. - Researchers undertook this retrospective cohort analysis among ST elevation myocardial infarction (STEMI) patients following primary percutaneous coronary intervention (pPCI), to assess if clinical outcomes in STEMI patients could be predicted by the Controlling Nutritional Status (CONUT) score. Major adverse cardiac event (MACE) was the endpoint. Three groups of patients were defined: normal (CONUT score 0–1; n = 278), mild–moderate (score 2–4; n = 418), and severe (score ≥ 5; n = 55) groups. In the normal, mild–moderate, and severe group, the incidence of MACEs was estimated to be 6.1%, 5.5%, and 45.5%, respectively. The significantly highest rate of MACE, myocardial re-infarction, and vessel revascularisation, was evident in patients with a CONUT score ≥ 5, as shown by Kaplan–Meier curves. For MACE prediction, the C-statistic of the CONUT score was shown to be 0.692, which was close to that of Global Registry of Acute Coronary Events. Overall, it was concluded that clinical results in STEMI patients can be independently predicted by the nutritional status assessed by the CONUT score, this indicates the relevance of active nutritional management for these patients post-PCI.
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