Zhang L, Chen S, Kang Y, et al. - Researchers undertook this prospective cohort analysis to assess the utility of trichrome sign, confetti-like depigmentation, and Koebner phenomenon in evaluating disease progression, severity, as well as prognosis in patients having vitiligo. From the outpatient department of Huashan Hospital, Fudan University in Shanghai, China, a total of 425 patients with vitiligo were selected. Experts focused on disease progression, severity, as well as prognosis during a 12-month span. Of overall participants, 425 completed the 12-month follow-up. Findings revealed a likely association between the presence of a clinical marker and worse prognosis and rapid disease progression among patients with vitiligo. More intensive therapy may be needed for patients with multiple clinical markers.