Gobbi G, et al. - Via this systematic review and meta-analysis of 11 studies that included 23,317 individuals, researchers estimated the extent to which cannabis use during adolescence is associated with the risk of developing subsequent major depression, anxiety, and suicidal behavior in young adulthood. They found an association of adolescent cannabis consumption with increased risk of developing depression and suicidal behavior later in life, even in the absence of a premorbid condition. They identified no association with anxiety. These findings supported the prevention of cannabis use in preadolescents and adolescents, and may inform public health policy and governments to apply preventive strategies to reduce the use of cannabis among youth.